Cotrimoxazole Dose for Children

Trimethoprim-SulfamethoxazoleOral

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Cotrimoxazole

Trimethoprim-Sulfamethoxazole

💊 Used for: UTIs, PCP prophylaxis, otitis media

Formulation

Suspension

200mg SMX/40mg TMP per 5ml

Dose Range

24 mg/kg

Max Daily

16 mg/kg

Frequency

Every 12 hours

Max Single

160 mg

Route: Oral

Dose by Child Weight

Based on formulation: 200mg SMX/40mg TMP per 5ml

Child's WeightDose (mg)Dose (ml)Max Daily Dose (mg)
5 kg1020 mg0.30.5 ml≤ 80 mg
6 kg1224 mg0.30.6 ml≤ 96 mg
7 kg1428 mg0.30.7 ml≤ 112 mg
8 kg1632 mg0.40.8 ml≤ 128 mg
9 kg1836 mg0.50.9 ml≤ 144 mg
10 kg2040 mg0.51.0 ml≤ 160 mg
12 kg2448 mg0.61.2 ml≤ 192 mg
15 kg3060 mg0.81.5 ml≤ 240 mg
18 kg3672 mg0.91.8 ml≤ 288 mg
20 kg4080 mg1.02.0 ml≤ 320 mg
25 kg50100 mg1.32.5 ml≤ 400 mg
30 kg60120 mg1.53.0 ml≤ 480 mg

* Always verify with your doctor. doses are approximate and may vary based on condition and formulation.

⚠️ Important Warnings

  • Monitor for rash
  • Check for G6PD deficiency
  • May cause photosensitivity

Possible Side Effects

  • Nausea, vomiting, skin rash
  • Hyperkalemia (especially in HIV)
  • Bone marrow suppression
  • Stevens-Johnson syndrome (rare)
  • Hepatotoxicity
  • Asymptomatic hyperbilirubinemia

💡 Use the DoseCare Calculator for interactive dose calculations tailored to your child's exact weight and formulation.

DoseCare is a decision support tool only. Always verify doses with a qualified healthcare provider.

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